June 24, 2013 1:43 AM EDT
It's a tie for me. The time I finally beat Shao Kahn in the end of the newest Mortal Kombat on the hardest difficulty was exhilarating-considering he was OP to the max. That is tied to the satisfaction I got for beating Red on Mount Silver in Pokemon Silver as a kid. An honorable mention goes to Skyrim the time I killed that bastard Nazeem in a creative fashion (which involved Soul Trap+Fear+Ignite+Ash Shell).