As someone who reviewed Uncharted 4 (amateur), I loved the experience of playing it—the climbing, the graphics and everything—but I was really underwhelmed by the story. It's so clearly The Last of Us in its tone and structure, but its cast can't support the same level of character drama. The Last of Us had Joel, the grouchy, grieving old man, and Ellie, the sarcastic, 'with it' heart of the story: There was a contrast there.
With Uncharted 4 we get Nate, the SNES era mascot platformer archetype with a whole lotta quips, and (mostly) Sam, who, while he's not exactly Joel, is basically just Joel (voice actor and all). I really couldn't get behind this character dynamic, which lasted through the majority of the game. I just really don't think the tone works. Uncharted's snarky ravine-jumping guns-blazing pulp romp was not the place to examine mortality, mid life, and marriage.
But it's still a must-play game for everything else. The story is enjoyable if not notable.