At 100 Restoration the Poison Rune will cost 146-147 magicka without cost reducing perks and enchantments. With Adept Restoration it'l be cut in half, meaning 73-74 magicka per rune. So, my guess is not much, especially with Paralyze and Flesh Spells
At 100 Restoration the Poison Rune will cost 146-147 magicka without cost reducing perks and enchantments. With Adept Restoration it'l be cut in half, meaning 73-74 magicka per rune. So, my guess is not much, especially with Paralyze and Flesh Spells