I am very suprised I haven't stumbled across this build before.  I guess the lack of tags and the lack of "alchemist" in the title.

I am working on a Solstheim Breton (descendant of Amelie Bontecou), who has a lust for secret knowledge (Yeah, Mora). I had my eyes on great Power/shout builds (with conjuration)  but alchemy suddenly seems like a very rich first step. In keeping with her humble origins too - a lfd hunter, a thief outcast from Bujold's bunch. OK, back to Save 1. (It was a very fun start though.)